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NCT01455441

Does the GLP-1 Receptor Agonist (Victoza®) Improve the Metabolic Response to Physical Training in Patients With Type 2 Diabetes?

Completed Phase 4 Last updated 28 May 2015
What this trial tests

Phase 4 trial testing Training and liraglutide in Type 2 Diabetes in 40 participants. Completed in 1 June 2014.

Timeline
1 October 2011
Primary endpoint
1 June 2013
1 June 2014

Quick facts

Lead sponsorTina Vilsboll
PhasePhase 4
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposetreatment
Enrollment40
Start date1 October 2011
Primary completion1 June 2013
Estimated completion1 June 2014
Sites1 location across Denmark

Drugs / interventions tested

Conditions studied

Sponsor

Tina Vilsboll

Who can join

Adults 18 to 80, any sex, with Type 2 Diabetes. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Sponsor's own description

The objective of this study is to investigate the effects of physical training in patients with type 2 diabetes during treatment with the GLP-1 receptor agonist liraglutide (Victoza®) in a 16-weeks double-blinded, randomized placebo-controlled clinical trial. Hypothesis: Physical training leads to better metabolic control in type 2 diabetic patients when training is combined with liraglutide (Victoza®) treatment.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Effect of glucagon-like peptide-1 receptor agonists on glycemic control, and weight reduction in adults: A multivariate meta-analysis.
    Yeh TL, Tsai MC, Tsai WH, Tu YK, et al · · 2023 · cited 33× · PMID 36696429 · DOI 10.1371/journal.pone.0278685
  2. 53 <sup>rd</sup> EASD Annual Meeting of the European Association for the Study of Diabetes : Lisbon, Portugal, 11 - 15 September 2017.
    · 2017 · cited 17× · PMID 28795195 · DOI 10.1007/s00125-017-4350-z

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