3A-Register Zur Ambulanten Therapie Mit RAS-Inhibitoren in Patienten Mit Arterieller Hypertonie in Deutschland

NCT01454583 COMPLETED Results posted

In Germany nearly half of the population present elevated values of blood pressure, with - as a result of lifestyle factors and a growing average age - further increasing numbers. Consequences of arterial hypertension may be cardiovascular diseases, cerebrovascular events, and renal insufficiency. Thus, hypertension therapy focuses on the reduction of these complications. The aims of the 3A-registry are the characterization of outpatients with hypertension, their diagnostic procedures and medical treatment (esp. with renin inhibitors), therapy compliance and success, clinical events, and an assessment of overall guideline adherence in the treatment of these patients. Patients fulfilling the relevant criteria are enrolled and followed up by their general practitioner or medical specialist.

Details

Lead sponsor	Stiftung Institut fuer Herzinfarktforschung
Status	COMPLETED
Enrolment	15337
Start date	2008-10
Completion	2012-07

Conditions

• Arterial Hypertension

Interventions

• Aliskiren
• ACE-I/ARB
• No RAS-inhibition

Primary outcomes

• Efficacy of Hypertension Treatment on Systolic Blood Pressure (SBP) — baseline and 1 year
  Relative change of systolic office blood pressure since baseline, i.e. SBP at baseline minus SBP after 1 year, the difference divided by the baseline value, multiplied by 100
• Efficacy of Hypertension Treatment on Diastolic Blood Pressure (DBP) — Baseline and 1 year
  Relative change of diastolic office blood pressure since baseline, i.e. DBP at baseline minus DBP after 1 year, the difference divided by the baseline value, multiplied by 100
• Efficacy of Hypertension Treatment on Systolic Blood Pressure (SBP) — Baseline and 2 years
  Relative change of systolic office blood pressure since baseline, i.e. SBP at baseline minus SBP after 2 years, the difference divided by the baseline value, multiplied by 100
• Efficacy of Hypertension Treatment on Diastolic Office Blood Pressure (DBP) — Baseline and 2 years
  Relative change of diastolic office blood pressure since baseline, i.e. DBP at baseline minus DBP after 1 year, the difference divided by the baseline value, multiplied by 100
• Efficacy of Hypertension Treatment on Systolic Blood Pressure (SBP) — Baseline and 3 years
  Relative change of systolic office blood pressure since baseline, i.e. SBP at baseline minus SBP after 3 years, the difference divided by the baseline value, multiplied by 100
• Efficacy of Hypertension Treatment on Diastolic Blood Pressure (DBP) — Baseline and 3 years
  Relative change of diastolic office blood pressure since baseline, i.e. DBP at baseline minus DBP after 3 years, the difference divided by the baseline value, multiplied by 100