Who is sponsoring NCT01420562?

NCT01420562 is sponsored by Universitaire Ziekenhuizen KU Leuven.

What condition does NCT01420562 study?

NCT01420562 studies Allogeneic Hematopoietic Stem Cell Transplantation (HSCT).

What is the status of NCT01420562?

NCT01420562 is currently RECRUITING.

Last reviewed 2024-07-12 · How we verify

Pharmacokinetics of Posaconazole in Allogeneic Transplant Patients With Mucositis

NCT01420562 RECRUITING

The goal of this study is to calculate pharmacokinetic parameters and to evaluate the trough levels of posaconazole reached in patients with different stages of mucositis, due to chemotherapy and total body irradiation.

Details

Lead sponsor	Universitaire Ziekenhuizen KU Leuven
Status	RECRUITING
Enrolment	55
Start date	2011-09
Completion	2025-03

Conditions

Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

Interventions

blood sampling

Primary outcomes

Posaconazole plasma levels and area under the curve in patients with different stages of mucositis — Day 0 (day of transplantation), day +7, day +14
Plasma levels of posaconazole will be determined to calculate the area under the curve. These values will be correlated with the stage of mucositis, which will be assessed using citrulline monitoring in plasma. The stage of mucositis will also be assessed using the Daily Oral Mucositis Score (DMS) and Daily Gut Mucositis Score (DGS).

Countries

Belgium