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Consolidation Therapy With Autologous T Cells Genetically Targeted to the B Cell Specific Antigen CD19 in Patients With Chronic Lymphocytic Leukemia Following Upfront Chemotherapy With Pentostatin, Cyclophosphamide and Rituximab
The purpose of this Phase I study is to test the safety and effect of specially prepared cells collected from the patients called "modified T cells." We want to find a safe dose of modified T cells for patients who have disease remaining after initial chemotherapy. We also want to find out what effects these T cells have on you and your leukemia.
Details
| Lead sponsor | Memorial Sloan Kettering Cancer Center |
|---|---|
| Phase | PHASE1 |
| Status | COMPLETED |
| Enrolment | 13 |
| Start date | Mon Aug 22 2011 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Mon Jan 07 2019 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Leukemia
Interventions
- cyclophosphamide
- modified T cells
Countries
United States