NCT01414010 is a NA clinical trial of Trametes versicolor extract in Human Gut Microbiota, sponsored by Beth Israel Deaconess Medical Center.

Who is sponsoring NCT01414010?

NCT01414010 is sponsored by Beth Israel Deaconess Medical Center.

What drugs are being tested in NCT01414010?

Interventions in NCT01414010: Trametes versicolor extract, Saccharomyces boulardii, Amoxicillin.

What condition does NCT01414010 study?

NCT01414010 studies Human Gut Microbiota.

Is NCT01414010 still recruiting?

NCT01414010 is currently completed. Last updated 25 June 2017.

Are results published for NCT01414010?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2017-06-25 · How we verify

NCT01414010

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Mushroom Extract, S Boulardii and Amoxicillin on the Human Microbiome

Completed NA Results posted Last updated 25 June 2017

What this trial tests

NA trial testing Trametes versicolor extract in Human Gut Microbiota in 32 participants. Completed in 1 February 2012.

Timeline

1 August 2011

Primary endpoint
1 February 2012

1 February 2012

Quick facts

Lead sponsor	Beth Israel Deaconess Medical Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	basic science
Enrollment	32
Start date	1 August 2011
Primary completion	1 February 2012
Estimated completion	1 February 2012
Sites	1 location across United States

Drugs / interventions tested

Trametes versicolor extract
Saccharomyces boulardii — full drug profile →
Amoxicillin (amoxicillin) — full drug profile →

Conditions studied

Human Gut Microbiota — all drugs for Human Gut Microbiota →

Sponsor

Beth Israel Deaconess Medical Center

Who can join

Adults 18 to 39, any sex, with Human Gut Microbiota. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Bacteria Prevalence in Stool
Time frame: Day 0 to 56
The most prevalent bacterial genera within the study population Before Treatment: Average of Day -7 and Day 0 During Treatment: Average of Days 10 and 14 After Treatment: Average of Days 21, 28, and 56

Sponsor's own description

The purpose of this study is to compare and contrast the effects of a prebiotic (Trametes Versicolor), a probiotic (Saccharomyces boulardii) and an antibiotic (amoxicillin) on the gut microbiota of healthy volunteers. It is expected that treatment will result in the rapid and reproducible alterations in fecal microbiota that will spontaneously reverse in the weeks after treatment is discontinued.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Narrative Review: Bioactive Potential of Various Mushrooms as the Treasure of Versatile Therapeutic Natural Product.
Chopra H, Mishra AK, Baig AA, Mohanta TK, et al · · 2021 · cited 33× · PMID 34575766 · DOI 10.3390/jof7090728

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01414010 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Beth Israel Deaconess Medical Center
Last refreshed: 25 June 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01414010.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing