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Three Month Treatment of GHRH (Growth Hormone Releasing Hormone) in the Elderly
The purpose of the study is to evaluate the effect of a naturally occurring hormone, called Growth Hormone Releasing Hormone (GHRH) on the muscle, bone, and fat tissues of the body. GHRH stimulates the production of growth hormone (GH), which regulates the build up of many tissues in the body, including muscles and bones. Many elderly people have low levels of GH. The overall goal of this research is to determine the efficacy of GHRH to raise levels of GH and improve these body tissues. Healthy men and women age 65 and older will receive GHRH in four doses nightly for 12 weeks and assessed for changes in muscle strength, body mass, physical performance, and how the body uses sugar.
Details
| Lead sponsor | University of Pennsylvania |
|---|---|
| Phase | Phase 2 |
| Status | TERMINATED |
| Enrolment | 13 |
| Start date | 2011-05 |
| Completion | 2011-08 |
Conditions
- Hormone Deficiency
- Aging
Interventions
- Growth Hormone Releasing Hormone (GHRH )
Primary outcomes
- Muscle Strength — 12 weeks
Pre-drug and post-drug 1 RM (Repetition Maximum) testing
Countries
United States