Who is sponsoring NCT01397331?

NCT01397331 is sponsored by Sheba Medical Center.

What drugs are being tested in NCT01397331?

Interventions in NCT01397331: Isoflurane, Propofol.

What condition does NCT01397331 study?

NCT01397331 studies Heart; Dysfunction Postoperative, Cardiac Surgery, Disorder; Heart, Functional, Postoperative, Cardiac Surgery.

Is NCT01397331 still recruiting?

NCT01397331 is currently terminated. Last updated 24 April 2018.

Last reviewed 2018-04-24 · How we verify

NCT01397331

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Influence of Anesthesia on Mechanical Efficiency of Left Ventricle in Patients Undergoing Open Heart Surgery

Terminated Phase 4 Last updated 24 April 2018

What this trial tests

Phase 4 trial testing Isoflurane in Heart; Dysfunction Postoperative, Cardiac Surgery in 28 participants. Terminated before completion.

Timeline

1 July 2010

Primary endpoint
27 June 2012

27 June 2012

Quick facts

Lead sponsor	Sheba Medical Center
Phase	Phase 4
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	28
Start date	1 July 2010
Primary completion	27 June 2012
Estimated completion	27 June 2012
Sites	1 location across Israel

Drugs / interventions tested

Isoflurane (ISOFLURANE) — full drug profile →
Propofol (Propofol) — full drug profile →

Conditions studied

Heart; Dysfunction Postoperative, Cardiac Surgery — all drugs for Heart; Dysfunction Postoperative, Cardiac Surgery →
Disorder; Heart, Functional, Postoperative, Cardiac Surgery — all drugs for Disorder; Heart, Functional, Postoperative, Cardiac Surgery →

Sponsor

Sheba Medical Center

Who can join

18 and older, any sex, with Heart; Dysfunction Postoperative, Cardiac Surgery or Disorder; Heart, Functional, Postoperative, Cardiac Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to delineate and compare the changes in coupled mechanical properties of left ventricle and arterial vascular bed caused by two popular anesthetic protocols commonly used in cardiac surgery (intravenous, based on the infusion of propofol, versus inhalational, based on isoflurane) on different stages of the surgery.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Isoflurane

Trials testing the same drug.

NCT07460050 — Comparison of Two Sedative Agents in Terms of Controlled Hypotension · NA · not yet recruiting
NCT07152912 — Impact of Isoflurane and Sevoflurane on Oxidative Stress in Patients Undergoing Laparoscopic Cholecystectomy · NA · recruiting
NCT06624592 — Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium · Phase 3 · recruiting
NCT05830864 — Multicenter Retrospective Study of Isoflurane in Refractory and Super-Refractory Status Epilepticus · completed
NCT06311604 — Evaluation of the Safety of Inhaled Sedation With Isoflurane in Head Trauma Patients · NA · recruiting

Other Sheba Medical Center trials

Trials by the same sponsor.

NCT07401524 — Carbetocin Uterotonic Treatment in Twin Pregnancies for Prevention of Postpartum Hemorrhage · Phase 4 · not yet recruiting
NCT07523373 — Facial Nerve Monitoring During Parotid and Facial Surgery Using a Non-Invasive Patch · NA · not yet recruiting
NCT07509229 — 9-cis Beta-Carotene-Rich Extract of Dunaliella Alga in Retinitis Pigmentosa Patients · Phase 1, PHASE2 · not yet recruiting
NCT07405723 — Arm Position and Blood Pressure Measurement Accuracy During Pregnancy · NA · recruiting
NCT07474987 — Portable VR-based Chromatic Pupilloperimeter for Diagnosis and Monitoring of Traumatic Brain Injury · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01397331 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Sheba Medical Center
Last refreshed: 24 April 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01397331.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing