Headache Inducing Characteristics and Possible Changes in Cerebral Blood Flow After Administration of Prostaglandin E2 in Migraine Suffers Without Aura.

NCT01384812 NA COMPLETED

The hypothesis of this study is that Prostaglandin E2 (PGE2) induces headache and dilatation of brain vessels in migraine patients without aura.

Details

Lead sponsor	Troels Wienecke
Phase	NA
Status	COMPLETED
Enrolment	12
Start date	2010-09
Completion	2011-07

Conditions

• "Migraine-like" Headache

Interventions

• dinoprostone
• isoton sodium chloride

Primary outcomes

• Headache score on a 10-point verbal rating scale (VRS). — 24 h
  Incidence of headache 0 indicated no headache; 1 indicated a different sensation, pounding or throbbing, but not necessarily painful; 5 indicated moderate headache and 10 indicated worst imaginable headache.

Countries

Denmark