Evaluation of the Effect of Atorvastatin and Pioglitazone in Carotid Atherosclerosis With the Use of 18Fluoride-Fludeoxyglucose(FDG) Positron Emission Tomography-computed Tomography (PET-CT)Imaging (PIONEER)

NCT01341730 Phase 4 TERMINATED Results posted

This study is a prospective randomized clinical trial and to compare the antiinflammatory effect of atorvastatin single therapy and atorvastatin and pioglitazone combination therapy in carotid arteries of stable and unstable angina patients by PET/CT.

Details

Lead sponsor	The Catholic University of Korea
Phase	Phase 4
Status	TERMINATED
Enrolment	41
Start date	2011-06
Completion	2012-08

Conditions

• Atherosclerosis
• Coronary Artery Disease

Interventions

• Atorvastatin 20mg
• Atorvastatin 20 mg + Pioglitazone 30 mg

Primary outcomes

• Difference of Standardized Uptake Value (SUV) of Atherosclerotic Plaque in Carotid Artery by PET CT — 3 months

Countries

South Korea