NCT01341249 is a Phase 1 clinical trial of Experimental DW224aa in Healthy, sponsored by Seoul National University Hospital.

Who is sponsoring NCT01341249?

NCT01341249 is sponsored by Seoul National University Hospital.

What drugs are being tested in NCT01341249?

Interventions in NCT01341249: Experimental DW224aa, Experimental DW224a.

Is NCT01341249 still recruiting?

NCT01341249 is currently completed. Last updated 15 July 2011.

Last reviewed 2011-07-15 · How we verify

NCT01341249

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Trial to Compare the Pharmacokinetic Profiles of DW224aa (Aspartate) Tablet and DW224a (Hydrochloride) Capsule After a Single Oral Administration in Healthy Male Volunteers

Completed Phase 1 Last updated 15 July 2011

What this trial tests

Phase 1 trial testing Experimental DW224aa in Healthy in 32 participants. Completed.

Timeline

1 April 2011

Primary endpoint
1 May 2011

Quick facts

Lead sponsor	Seoul National University Hospital
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Enrollment	32
Start date	1 April 2011
Primary completion	1 May 2011
Sites	1 location across South Korea

Drugs / interventions tested

Experimental DW224aa — full drug profile →
Experimental DW224a — full drug profile →

Conditions studied

Healthy — all drugs for Healthy →

Sponsor

Seoul National University Hospital

Who can join

Adults 20 to 45, male only, with Healthy. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Cmax of zabofloxacin in plasma
Time frame: Up to 48
AUClast of zabofloxacin in plasma
Time frame: Up to 48

Sponsor's own description

The purpose of this study is to compare and explore pharmacokinetics of zabofloxacin, the main component of DW224aa(Test drug) and DW224a(Reference drug).

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Delafloxacin, Finafloxacin, and Zabofloxacin: Novel Fluoroquinolones in the Antibiotic Pipeline.
Kocsis B, Gulyás D, Szabó D. · · 2021 · cited 35× · PMID 34943718 · DOI 10.3390/antibiotics10121506
Emerging Treatment Options for Infections by Multidrug-Resistant Gram-Positive Microorganisms.
Koulenti D, Xu E, Song A, Sum Mok IY, et al · · 2020 · cited 27× · PMID 32019171 · DOI 10.3390/microorganisms8020191
Comparison of pharmacokinetics between new quinolone antibiotics: the zabofloxacin hydrochloride capsule and the zabofloxacin aspartate tablet.
Han H, Kim SE, Shin KH, Lim C, et al · · 2013 · cited 14× · PMID 23865727 · DOI 10.1185/03007995.2013.825591

Verify or expand the search:

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Other Seoul National University Hospital trials

Trials by the same sponsor.

NCT07262944 — EOI Block in Otoplasty With Rib Cartilage Graft · NA · recruiting
NCT07464210 — Nemtabrutinib, Bortezomib, and Rituximab for WM · Phase 2 · not yet recruiting
NCT07550803 — Effect of Intraoperative Dexamethasone on Early Postoperative Sleep Quality in Patients Undergoing Nasal Surgery · NA · not yet recruiting
NCT07522138 — Home-based Self-exercise in Patients With Parkinson's Disease: A Feasibility Study · NA · not yet recruiting
NCT07476651 — Scout Dose of Resin Microspheres · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01341249 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Seoul National University Hospital
Last refreshed: 15 July 2011

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01341249.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing