Last reviewed · How we verify

NCT01329926

Molecular Analysis of Human Neural Stem Cells

Withdrawn Last updated 12 April 2022
What this trial tests

trial testing Harvesting of neural stem cells in Parkinson's Disease. Withdrawn.

Timeline
30 June 2011
Primary endpoint
31 December 2022
31 December 2023

Quick facts

Lead sponsorNeuroGeneration
StatusWithdrawn
Study typeOBSERVATIONAL
Start date30 June 2011
Primary completion31 December 2022
Estimated completion31 December 2023
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

NeuroGeneration — full company profile →

Who can join

Adults 35 to 85, any sex, with Parkinson's Disease or Parkinsonism. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to develop and optimize methods to isolate, propagate and differentiate adult human neural stem cells from patients with degenerative neurological disorders like Parkinson's disease.

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Current concept in neural regeneration research: NSCs isolation, characterization and transplantation in various neurodegenerative diseases and stroke: A review.
    Vishwakarma SK, Bardia A, Tiwari SK, Paspala SA, et al · · 2014 · cited 68× · PMID 25685495 · DOI 10.1016/j.jare.2013.04.005
  2. An activated protein C analog stimulates neuronal production by human neural progenitor cells via a PAR1-PAR3-S1PR1-Akt pathway.
    Guo H, Zhao Z, Yang Q, Wang M, et al · · 2013 · cited 51× · PMID 23554499 · DOI 10.1523/jneurosci.4491-12.2013
  3. Stem cell transplantation in neurological diseases: improving effectiveness in animal models.
    Adami R, Scesa G, Bottai D. · · 2014 · cited 27× · PMID 25364724 · DOI 10.3389/fcell.2014.00017
  4. Treating non-motor symptoms of Parkinson's disease with transplantation of stem cells.
    Pantcheva P, Reyes S, Hoover J, Kaelber S, et al · · 2015 · cited 20× · PMID 26394528 · DOI 10.1586/14737175.2015.1091727
  5. Neural Cells for Neurodegenerative Diseases in Clinical Trials.
    Fan Y, Goh ELK, Chan JKY. · · 2023 · cited 17× · PMID 37487111 · DOI 10.1093/stcltm/szad041
  6. Current Status of Stem Cell-Derived Therapies for Parkinson's Disease: From Cell Assessment and Imaging Modalities to Clinical Trials.
    Jang SE, Qiu L, Chan LL, Tan EK, et al · · 2020 · cited 16× · PMID 33177975 · DOI 10.3389/fnins.2020.558532

Verify or expand the search:

Other recruiting trials for Parkinson's Disease

Currently open trials in the same condition.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01329926.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing