NCT01328015 is a Phase 2 clinical trial of Oxybutynin 5 mg pills in Hyperhidrosis, sponsored by Federal University of São Paulo.

Who is sponsoring NCT01328015?

NCT01328015 is sponsored by Federal University of São Paulo.

What drugs are being tested in NCT01328015?

Interventions in NCT01328015: Oxybutynin 5 mg pills.

What condition does NCT01328015 study?

NCT01328015 studies Hyperhidrosis.

Is NCT01328015 still recruiting?

NCT01328015 is currently completed. Last updated 1 April 2011.

Last reviewed 2011-04-01 · How we verify

NCT01328015

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Use of Oxybutynin in Women After Thoracoscopic Sympathectomy and the Effect on Plantar Hyperhidrosis

Completed Phase 2 Last updated 1 April 2011

What this trial tests

Phase 2 trial testing Oxybutynin 5 mg pills in Hyperhidrosis in 32 participants. Completed in 1 June 2010.

Timeline

1 March 2010

Primary endpoint
1 May 2010

1 June 2010

Quick facts

Lead sponsor	Federal University of São Paulo
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	32
Start date	1 March 2010
Primary completion	1 May 2010
Estimated completion	1 June 2010

Drugs / interventions tested

Oxybutynin 5 mg pills — full drug profile →

Conditions studied

Hyperhidrosis — all drugs for Hyperhidrosis →

Sponsor

Federal University of São Paulo

Who can join

Adults 18 to 40, female only, with Hyperhidrosis. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

To evaluate the effect of oxybutynin in plantar hyperhidrosis
Time frame: 60 days
Apply the questionnaires of quality of life, specific ones for hyperhidrosis and TEWL before in patients with persistence of plantar sweating after thoracic sympathectomy. After continuous use of oxybutynin for a month, repeated them for comparison.

Sponsor's own description

A study in which the experimental treatment procedure is compared to a standard (control) treatment, The use of oxybutynin in the late postoperative thoracic sympathectomy for women: 1. To Evaluate the effect of oxybutynin on plantar hyperhidrosis. 2. To evaluate the effect of oxybutynin in compensatory hyperhidrosis. 3. To compare the results of questionnaires on quality of life and specific for hyperhidrosis to the results of TEWL.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Randomized trial - oxybutynin for treatment of persistent plantar hyperhidrosis in women after sympathectomy.
Costa Ada S, Leão LE, Succi JE, Perfeito JA, et al · · 2014 · cited 22× · PMID 24519200 · DOI 10.6061/clinics/2014(02)05
Clinical Measurement of Transepidermal Water Loss.
Kundu D, Jayaraman A, Sen CK. · · 2026 · cited 4× · PMID 40476522 · DOI 10.1089/wound.2024.0148
Hyperhidrosis Clinical Trial Disparities: Enrollment and Reporting Trends.
Gawey L, Joshi A, Dagenet CB, Price KN, et al · · 2025 · PMID 40539206 · DOI 10.1159/000546318

Verify or expand the search:

Other recruiting trials for Hyperhidrosis

Currently open trials in the same condition.

NCT05805696 — Treatment and Mapping of Impostor Phenomenon · NA · recruiting
NCT05102396 — Topical Oxybutynin for Treatment of Hyperidrosis: Local or Systemic Effect? · Phase 2 · recruiting
NCT05403710 — Botulinum Toxin Therapy in Hidradenitis Suppurativa · recruiting

Other Federal University of São Paulo trials

Trials by the same sponsor.

NCT07376811 — Effect Of Sleeping Posture Guidance On Sleep Quality In Patients With Rotator Cuff Syndrome · NA · not yet recruiting
NCT06805656 — Multi Interventional Approaches to Mitigate HIV Reservoirs Aiming the Sustained HIV Remission Without Antiretrovirals · Phase 2 · not yet recruiting
NCT06970964 — Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before a · NA · completed
NCT06905860 — Intra-articular Infiltration of Platelet-Rich Fibrin vs Corticosteroid in Mild to Moderate Knee Osteoarthritis · Phase 4 · not yet recruiting
NCT06829992 — Effects of Applying Kinesio Tapping on Primary Dysmenorrhea in Football Players · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01328015 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Federal University of São Paulo
Last refreshed: 1 April 2011

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01328015.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing