NCT01320462

Smoking Cessation Program in the Preadmission Clinic:The Combination of Counseling, Pharmacotherapy and Quit Line

Completed NA Last updated 4 May 2017

What this trial tests

NA trial testing Smoking cessation counselling group in Smoking in 296 participants. Completed in 1 April 2017.

Timeline

1 December 2010

Primary endpoint
1 April 2017

1 April 2017

Quick facts

Lead sponsor	University Health Network, Toronto
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	296
Start date	1 December 2010
Primary completion	1 April 2017
Estimated completion	1 April 2017
Sites	2 locations across Canada

Drugs / interventions tested

• Smoking cessation counselling group — full drug profile →
• Control group:

Conditions studied

• Smoking — all drugs for Smoking →

Sponsor

University Health Network, Toronto

Who can join

18 and older, any sex, with Smoking. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

• pre-surgery counseling for quit smoking
  Time frame: 1 year after surgery
  In order to determine the prevalence of abstinence in long-term follow up (4, 12, 24 and 52 weeks), patients will be asked the following questions: * Have you been abstinent from smoking for the past four weeks? (4-week abstinence) * Do you currently smoke cigarettes everyday? (point prevalence) * Have you been abstinent from smoking since the last time you quit smoking? (continuous abstinence)

Sponsor's own description

Main Hypothesis: The multifaceted intervention (preoperative counseling, pharmacotherapy by varenicline and follow up by quit line) in the preoperative clinic is more effective than the simple preoperative smoking intervention (brief advice and provision of information about the quit lines ) in terms of short-term and long-term quit rates

Objectives: To evaluate the effectiveness and feasibility of a multifaceted intervention (preoperative counseling, pharmacotherapy by varenicline and follow up by the quit line) in the preoperative clinic to help surgical patients quit smoking perioperatively and for the long-term.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Combined pharmacotherapy and behavioural interventions for smoking cessation.
   Stead LF, Koilpillai P, Fanshawe TR, Lancaster T. · · 2016 · cited 335× · PMID 27009521 · DOI 10.1002/14651858.cd008286.pub3
2. Nicotine receptor partial agonists for smoking cessation.
   Cahill K, Lindson-Hawley N, Thomas KH, Fanshawe TR, et al · · 2016 · cited 228× · PMID 27158893 · DOI 10.1002/14651858.cd006103.pub7