Last reviewed · How we verify
NCT01312610: OJOC
Effect of Chronic Orange Juice Consumption on Cognitive Function in Healthy Older Adults
NA trial testing High flavanone orange juice in Nerve Degeneration in 40 participants. Completed in 1 September 2011.
1 August 2011
Quick facts
| Lead sponsor | University of Reading |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 40 |
| Start date | 1 September 2010 |
| Primary completion | 1 August 2011 |
| Estimated completion | 1 September 2011 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- High flavanone orange juice
- Control orange juice
Conditions studied
- Nerve Degeneration — all drugs for Nerve Degeneration →
Sponsor
University of Reading
Who can join
Adults 60 to 75, any sex, with Nerve Degeneration. Healthy volunteers can join.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Executive function - Attention
Time frame: change in attention from baseline and 8 weeks
Assessment by human cognitive test battery delivered by computer and human operator. Assessments will be carried out at baseline and at the end of each intervention arm.
Sponsor's own description
This study is investigating the effect of 8 weeks of orange juice supplementation on executive function in healthy older adults. The study is a controled, double-blind, crossover trial and involves a 8 week supplementation with a high flavonone orange juice and a carbohydrate-matched control. Volunteers consume 500ml of either the test juice or the control juice per day for an 8 week period. There is then an 8 week washout period before subjects proceed to the other arm of the study. Subjects are randomly assigned to either arm at the beginning of the study. Measures of cognitive function will be administered pre and post both test and control interventions. Blood pressure will also be measured and blood and urine samples will be collected to assess absorption of from the juice. A sub-sample of volunteers will undergo MRI imaging pre- and post intervention to acquire cerebral blow flow information.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT01312610
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Nerve Degeneration
Currently open trials in the same condition.
- NCT05091112 — Nerve Composition of Human Lumbar Dorsal Primary Rami and Its Medial Branch · recruiting
Other University of Reading trials
Trials by the same sponsor.
- NCT07499414 — The Effects of the Bile Acid Supplement, 7-keto Lithocholic Acid, on Human Gut Microbiota and Risk Factors for Disease. · NA · recruiting
- NCT07401212 — GUTLINK4KIDS Intervention · NA · recruiting
- NCT07006909 — Hair Isotope Analysis for Early Cancer Detection · not yet recruiting
- NCT06832488 — Food Texture, Eating Rate and Food Intake in Care Home Older Adults. · NA · completed
- NCT07056634 — The Effects of Nature-Based Activity vs. Indoor Exercise on Cognition, Psychological, and Physiological Health · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01312610 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Reading
- Last refreshed: 22 November 2011
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01312610.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing