Who is sponsoring NCT01287780?

NCT01287780 is sponsored by Oslo University Hospital.

What condition does NCT01287780 study?

NCT01287780 studies Surgical Wound Infection.

What drugs are being tested in NCT01287780?

Interventions: Collagen-gentamicin sponge.

What is the status of NCT01287780?

NCT01287780 is currently COMPLETED.

Last reviewed 2013-08-15 · How we verify

Local Gentamicin Application to Reduce Postoperative Infection Rate in Hemiarthroplasty After Fracture of the Proximal Femur: a Randomized Controlled Trial

NCT01287780 Phase 3 COMPLETED

The majority of elderly patients with a displaced fracture of the proximal femur are now treated with a hemiarthroplasty. Prosthetic joint infection is a devastating complication, and the infection rate is high in this group of elderly patients. Local application of gentamicin produces high antibiotic concentrations in the wound. The aim of this study is to determine whether locally administered collagen-gentamicin in the joint perioperatively in addition to routine IV prophylaxis with beta-lactam antibiotics can reduce the early postoperative infection rate (\< 4 weeks postoperative)after hemiarthroplasty in proximal femoral fractures.

Details

Lead sponsor	Oslo University Hospital
Phase	Phase 3
Status	COMPLETED
Enrolment	800
Start date	2011-01
Completion	2013-08

Conditions

Surgical Wound Infection

Interventions

Collagen-gentamicin sponge

Primary outcomes

Number of patients with postoperatively infection after hemiarthroplasty to evaluate locally administered collagen-gentamicin peroperatively — Within 4 weeks after prosthetic surgery
A randomized multicentre trial

Countries

Norway