A 3-month, Observational Study Investigating With Electronic Monitoring the Level of Adherence and Treatment Satisfaction With Latanoprost/Timolol Fixed Combination Versus Unfixed Therapy in Open-angle Glaucoma

NCT01281020 COMPLETED

A 6-month, parallel, non-interventional trial investigating the level of adherence and the impact of dosing in open-angle glaucoma patients who receive either unfixed therapy with latanoprost once in the evening and timolol twice daily, or latanoprost/timolol fixed combination therapy once in the evening. All patients participating in this observational study will be monitored for their adherence with the use of Medication Event Monitoring System (MEMS). At the end of treatment periods treatment satisfaction will be assessed with selected questions from the Treatment Satisfaction Survey-Intraocular Pressure survey. This study will monitor objectively, for the first time, adherence and intraocular pressure control with fixed versus unfixed therapy. Finally it will help us to elucidate the impact of dosing (once-a-day versus three-times-daily) on the level of adherence in glaucoma.

Details

Lead sponsor	Aristotle University Of Thessaloniki
Status	COMPLETED
Enrolment	132
Start date	2009-05
Completion	2011-07

Conditions

• Primary Open-angle Glaucoma
• Ocular Hypertension
• Exfoliation Glaucoma

Primary outcomes

• Rate of adherence — 6 months
  Rate of asherence with fixed vs unfixed glaucoma therapy

Countries

Greece