NCT01273220

National Epidemiologic Survey on Alcohol and Related Conditions-III

Completed Last updated 21 August 2020

What this trial tests

trial in Alcohol-Related Disorders in 36,309 participants. Completed in 18 August 2020.

Timeline

7 January 2011

Primary endpoint
26 September 2013

18 August 2020

Quick facts

Lead sponsor	National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Status	Completed
Study type	OBSERVATIONAL
Enrollment	36,309
Start date	7 January 2011
Primary completion	26 September 2013
Estimated completion	18 August 2020
Sites	1 location across United States

Conditions studied

• Alcohol-Related Disorders — all drugs for Alcohol-Related Disorders →

Sponsor

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Who can join

18 and older, any sex, with Alcohol-Related Disorders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background:

\- Alcohol use disorders are the most prevalent mental disorders in the United States and are a factor in more than 10 percent of all deaths, including heart disease, stroke, and certain types of cancer and chronic illness. Research into better treatment methods for alcohol use disorders and their associated disabilities requires a broad amount of information on the genetic and environmental factors that predispose certain individuals to alcoholism. To improve the quality of available information for research, the National Institutes of Health is conducting a nationwide survey on alcohol use disorders and related physical and mental disabilities, and will collect genetic information through saliva samples.

Objectives:

\- To collect interview data and saliva samples from the U.S. civilian noninstitutionalized population, 18 years and older, in order to study the extent of and contributing factors to alcohol use and abuse in the United States.

Eligibility:

\- Individuals at least 18 years of age who do not live in institutions (i.e., prisons, inpatient mental hospitals) and who are willing to be interviewed in English, Spanish, and the four most commonly spoken Asian languages in the United States (e.g., Chinese, Korean).

Design:

* The study will involve three main components: an automated computer-assisted interview, an automated questionnaire, and the collection of a saliva sample.
* Participants will be recruited through community through publically available U.S. Census Bureau files.
* The interview and questionnaire will ask standardized questions related to personal history; alcohol use and possible disorders; symptoms scales of mood, anxiety, and eating conditions that frequently co-occur with alcohol and drug use disorders; tobacco, medicine and drug use and disorders; selected personality traits, including behavior; alcohol, drug, and mental health treatment utilization; and medical conditions related to alcohol consumption.
* Participants will provide a saliva sample for genetic study.

Background:

\- Alcohol use disorders are the most prevalent mental disorders in the United States and are a factor in more than 10 percent of all deaths, including heart disease, stroke, and certain types of cancer and chronic illness. Research into better treatment methods for alcohol use disorders and their associated disabilities requires a broad amount of information on the genetic and environmental factors that predispose certain individuals to alcoholism. To improve the quality of available information for research, the National Institutes of Health is conducting a nationwide survey on alcohol use disorders and related physical and mental disabilities, and will collect genetic information through saliva samples.

Objectives:

\- To collect interview data and saliva samples from the U.S. civilian noninstitutionalized population, 18 years and older, in order to study the extent of and contributing factors to alcohol use and abuse in the United States.

Eligibility:

\- Individuals at least 18 years of age who do not live in institutions (i.e., prisons, inpatient mental hospitals) and who are willing to be interviewed in English, Spanish, and the four most commonly spoken Asian languages in the United States (e.g., Chinese, Korean).

Design:

* The study will involve three main components: an automated computer-assisted interview, an automated questionnaire, and the collection of a saliva sample.
* Participants will be recruited through community through publically available U.S. Census Bureau files.
* The interview and questionnaire will ask standardized questions related to personal history; alcohol use and possible disorders; symptoms scales of mood, anxiety, and eating conditions that frequently co-occur with alcohol and drug use disorders; tobacco, medicine and drug use and disorders; selected personality traits, including behavior; alcohol, drug, and mental health treatment utilization; and medical conditions related to alcohol consumption.
* Participants will provide a saliva sample for genetic study.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Differences in diagnostic rules used to determine borderline personality disorder impact prevalence and associations with clinically relevant variables: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions-III.
   Loya JM, Wagner A, Pittman B, Davis MT. · · 2024 · cited 2× · PMID 38206863 · DOI 10.1037/per0000643