NCT01271478 is a Phase 4 clinical trial of Telmisartan plus Captopril in Inflammation, sponsored by Coordinación de Investigación en Salud, Mexico.

Who is sponsoring NCT01271478?

NCT01271478 is sponsored by Coordinación de Investigación en Salud, Mexico.

What drugs are being tested in NCT01271478?

Interventions in NCT01271478: captopril plus placebo, telmisartan plus placebo, Telmisartan plus Captopril, Placebo.

What condition does NCT01271478 study?

NCT01271478 studies Inflammation, End-stage Renal Disease.

Is NCT01271478 still recruiting?

NCT01271478 is currently completed. Last updated 18 December 2018.

Last reviewed 2018-12-18 · How we verify

NCT01271478

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Telmisartan and Captopril on Systemic Inflammation of Patients on Hemodialysis

Completed Phase 4 Last updated 18 December 2018

What this trial tests

Phase 4 trial testing captopril plus placebo in Inflammation in 60 participants. Completed in 31 August 2013.

Timeline

1 August 2009

Primary endpoint
1 December 2010

31 August 2013

Quick facts

Lead sponsor	Coordinación de Investigación en Salud, Mexico
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	60
Start date	1 August 2009
Primary completion	1 December 2010
Estimated completion	31 August 2013
Sites	1 location across Mexico

Drugs / interventions tested

captopril plus placebo — full drug profile →
telmisartan plus placebo — full drug profile →
Telmisartan plus Captopril — full drug profile →
Placebo

Conditions studied

Inflammation — all drugs for Inflammation →
End-stage Renal Disease — all drugs for End-stage Renal Disease →

Sponsor

Coordinación de Investigación en Salud, Mexico — full company profile →

Who can join

Adults 18 to 70, any sex, with Inflammation or End-stage Renal Disease. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Serum concentrations of TNF-a, IL-6 and CRP
Time frame: 3 months

Sponsor's own description

The aim of this study was to compare the dual use of telmisartan and captopril vs the individual use of such drugs and placebo on the systemic inflammation of patients on hemodialysis (HD).

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Randomized, double-blinded, controlled clinical trial of the effect of captopril, telmisartan and their combination on systemic inflammation of patients on hemodialysis.
Ordaz-Medina SM, Cueto-Manzano AM, González-Plascencia J, Montañez-Fernández JL, et al · · 2022 · cited 1× · PMID 36266534 · DOI 10.1038/s41598-022-22656-5

Verify or expand the search:

Other recruiting trials for Inflammation

Currently open trials in the same condition.

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Other Coordinación de Investigación en Salud, Mexico trials

Trials by the same sponsor.

NCT07248813 — Telerehabilitation Program to Improve Function in People With Chronic Low Back Pain Compared With Conventional Care · NA · recruiting
NCT07248891 — Type 2 Diabetes and Associated Factors in Mexico · enrolling by invitation
NCT06847373 — Efficacy and Safety of Vitamin D Supplementation in Pediatric Patients with Obesity · NA · recruiting
NCT07248761 — Early Hydrocortisone Versus Regular Treatment in Shock in Extremely Preterm Neonates - an Open Randomized Controlled Tri · Phase 4 · active not recruiting
NCT06782737 — Mediterranean Diet Versus Standard Diet on Candiormetabolic Indicator in Patients With Apnea · NA · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01271478 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Coordinación de Investigación en Salud, Mexico
Last refreshed: 18 December 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01271478.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing