Who is sponsoring NCT01199458?

NCT01199458 is sponsored by Region Örebro County.

What condition does NCT01199458 study?

NCT01199458 studies Lower Esophageal Sphincter.

What drugs are being tested in NCT01199458?

Interventions: alfentanil, saline.

What is the status of NCT01199458?

NCT01199458 is currently COMPLETED.

Last reviewed 2016-11-08 · How we verify

The Effect of Alfentanil on the Lower Esophageal Sphincter During Anesthesia Induction - a Study in Volunteers

NCT01199458 Phase 4 COMPLETED

This study evaluates the effects of adding an opioid (alfentanil) during anesthesia induction with respect to the barrierpressure in the esophagogastric junction. The secondary aim was to investigate whether the effect of cricoid pressure influences the barrierpressure.

Details

Lead sponsor	Region Örebro County
Phase	Phase 4
Status	COMPLETED
Enrolment	17
Start date	2010-09
Completion	2010-10

Conditions

Lower Esophageal Sphincter

Interventions

alfentanil
saline

Primary outcomes

Changes in barrierpressure (in mmHg) in the area of the lower esophageal sphincter. — 1 min after the application of the induction agent (propofol)
Pressure variations in the lower esophageal sphincter will be measured continuously during the whole study. Registrations will be saved in the computer-software. Predetermined time points will be marked on the registrations for later evaluation.

Countries

Sweden