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NCT01196845: ADISAS

Inflammation and Oxidative Stress of Adipose Tissue in Sleep Apnea Syndrome

Terminated NA Last updated 29 December 2025
What this trial tests

NA trial testing cPAP in Decrease of Inflammation of Adipose Tissue in 40 participants. Terminated before completion.

Timeline
16 October 2010
Primary endpoint
16 February 2017
16 February 2017

Quick facts

Lead sponsorUniversity Hospital, Grenoble
PhaseNA
StatusTerminated
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposebasic science
Enrollment40
Start date16 October 2010
Primary completion16 February 2017
Estimated completion16 February 2017
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

University Hospital, Grenoble

Who can join

Adults 18 to 69, male only, with Decrease of Inflammation of Adipose Tissue or Sleep Apnea Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main objective of this study is to evaluate the decrease of inflammation of adipose tissue in obese and non-obese patients having a sleep apnea syndrome and treated or not by continuous positive airway pressure (cPAP). An interim analysis will be performed when 40 patients will be included.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Impact of effective versus sham continuous positive airway pressure on liver injury in obstructive sleep apnoea: Data from randomized trials.
    Jullian-Desayes I, Tamisier R, Zarski JP, Aron-Wisnewsky J, et al · · 2016 · cited 44× · PMID 26567858 · DOI 10.1111/resp.12672

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Other University Hospital, Grenoble trials

Trials by the same sponsor.

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