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NCT01196845: ADISAS
Inflammation and Oxidative Stress of Adipose Tissue in Sleep Apnea Syndrome
NA trial testing cPAP in Decrease of Inflammation of Adipose Tissue in 40 participants. Terminated before completion.
16 February 2017
Quick facts
| Lead sponsor | University Hospital, Grenoble |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 40 |
| Start date | 16 October 2010 |
| Primary completion | 16 February 2017 |
| Estimated completion | 16 February 2017 |
| Sites | 1 location across France |
Drugs / interventions tested
- cPAP
- cPAP
- cPAP
- cPAP
Conditions studied
- Decrease of Inflammation of Adipose Tissue — all drugs for Decrease of Inflammation of Adipose Tissue →
- Sleep Apnea Syndrome — all drugs for Sleep Apnea Syndrome →
Sponsor
University Hospital, Grenoble
Who can join
Adults 18 to 69, male only, with Decrease of Inflammation of Adipose Tissue or Sleep Apnea Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The main objective of this study is to evaluate the decrease of inflammation of adipose tissue in obese and non-obese patients having a sleep apnea syndrome and treated or not by continuous positive airway pressure (cPAP). An interim analysis will be performed when 40 patients will be included.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Impact of effective versus sham continuous positive airway pressure on liver injury in obstructive sleep apnoea: Data from randomized trials.
Jullian-Desayes I, Tamisier R, Zarski JP, Aron-Wisnewsky J, et al · · 2016 · cited 44× · PMID 26567858 · DOI 10.1111/resp.12672
Verify or expand the search:
- PubMed search for NCT01196845
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT01196845 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Grenoble
- Last refreshed: 29 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01196845.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing