NCT01181908 is a Phase 1 clinical trial of single dose in Alcoholism, sponsored by GlaxoSmithKline.

Who is sponsoring NCT01181908?

NCT01181908 is sponsored by GlaxoSmithKline.

What drugs are being tested in NCT01181908?

Interventions in NCT01181908: single dose.

What condition does NCT01181908 study?

NCT01181908 studies Alcoholism.

Is NCT01181908 still recruiting?

NCT01181908 is currently completed. Last updated 27 June 2017.

Last reviewed 2017-06-27 · How we verify

NCT01181908

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Alcohol Interaction Study

Completed Phase 1 Last updated 27 June 2017

What this trial tests

Phase 1 trial testing single dose in Alcoholism in 21 participants. Completed in 30 December 2009.

Timeline

11 November 2009

Primary endpoint
30 December 2009

30 December 2009

Quick facts

Lead sponsor	GlaxoSmithKline
Phase	Phase 1
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	other
Enrollment	21
Start date	11 November 2009
Primary completion	30 December 2009
Estimated completion	30 December 2009
Sites	1 location across Netherlands

Drugs / interventions tested

single dose

Conditions studied

Alcoholism — all drugs for Alcoholism →

Sponsor

GlaxoSmithKline — full company profile →

Who can join

Adults 18 to 65, any sex, with Alcoholism. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is understand the effects of GSK114814 and alcohol in healthy volunteers when taken together.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Pharmacokinetics and central nervous system effects of the novel dual NK1 /NK3 receptor antagonist GSK1144814 in alcohol-intoxicated volunteers.
te Beek ET, Hay JL, Bullman JN, Burgess C, et al · · 2013 · cited 9× · PMID 23067311 · DOI 10.1111/bcp.12004

Verify or expand the search:

Other trials of single dose

Trials testing the same drug.

NCT00513565 — A Study To Investigate Effects Of GSK561679 On Brain Activation During Emotional Processing In Healthy Volunteers · Phase 1 · completed

Other recruiting trials for Alcoholism

Currently open trials in the same condition.

NCT06676059 — SMART-r: Substance Monitoring and Active Relapse Tracking Repository · recruiting
NCT06493773 — Alcohol Misuse Treatment to Patients Newly Diagnosed With Alcohol-related Liver Disease: a Randomized Controlled Trial · NA · recruiting
NCT07216872 — Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment of Alcohol Use · NA · recruiting
NCT07305701 — Cohort Study on Medical Students' Mental Health · recruiting
NCT06415721 — Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder · NA · recruiting

Other GlaxoSmithKline trials

Trials by the same sponsor.

NCT07569081 — A Study Evaluating the Efficacy and Safety of Momelotinib in Participants With Vacuoles, E1-enzyme, X-linked, Autoinflam · Phase 2, PHASE3 · not yet recruiting
NCT07406347 — A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Infants Receiving 3-dose · Phase 1 · not yet recruiting
NCT07286266 — A Study to Investigate GSK5733584 Compared With Chemotherapy in Participants With Platinum-resistant Ovarian Cancer (BEH · Phase 3 · not yet recruiting
NCT07286331 — A Study to Investigate GSK5733584 Compared With Chemotherapy in Participants With Recurrent Endometrial Cancer (BEHOLD-E · Phase 3 · not yet recruiting
NCT07406334 — A Trial to Evaluate the Safety and Reactogenicity of an Investigational Pneumococcal Vaccine in Toddlers 12 to 15 Months · Phase 1 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01181908 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by GlaxoSmithKline
Last refreshed: 27 June 2017

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01181908.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing