Who is sponsoring NCT01147653?

NCT01147653 is sponsored by Joanne Kurtzberg, MD.

What condition does NCT01147653 study?

NCT01147653 studies Cerebral Palsy, CP, Spastic Cerebral Palsy.

What drugs are being tested in NCT01147653?

Interventions: Autologous UCB Reinfusion, Placebo.

What is the status of NCT01147653?

NCT01147653 is currently COMPLETED.

Last reviewed 2026-04-15 · How we verify

Is Autologous Umbilical Cord Blood Reinfusion Beneficial in Children With Cerebral Palsy: A Randomized, Blinded, Placebo-Controlled, Crossover Study

NCT01147653 Phase 2 COMPLETED Results posted

The purpose of this study is to determine the efficacy of a single intravenous infusion of autologous umbilical cord blood (UCB) for the treatment of pediatric patients with spastic cerebral palsy.

Details

Lead sponsor	Joanne Kurtzberg, MD
Phase	Phase 2
Status	COMPLETED
Enrolment	63
Start date	2010-06
Completion	2016-03

Conditions

Cerebral Palsy
CP
Spastic Cerebral Palsy

Interventions

Autologous UCB Reinfusion
Placebo

Primary outcomes

Change in Gross Motor Function Measure 66 (GMFM-66) Score — Baseline to Year 1
Change in Gross Motor Function Measure 66 (GMFM-66) Score from Baseline to Year 1. The GMFM-66 is a clinical tool used to evaluate gross motor function in children with cerebral palsy and is scored using a propriety software program called the Gross Motor Ability Estimator (GMAE) that produces an interval level continuous score ranging from 0 to 100. Higher scores indicate better motor function. A negative change in GMFM-66 score indicates a reduction in motor function, a positive change indicates improvement in motor function, and zero indicates no change in motor function.

Countries

United States