Intermittent Preventive Treatment With Azithromycin-containing Regimens for the Prevention of Malarial Infections and Anaemia and the Control of Sexually Transmitted Infections in Pregnant Women in Papua New Guinea (IPTp in PNG)

NCT01136850 Phase 3 COMPLETED

The purpose of this study is to determine whether repeated courses of sulphadoxine-pyrimethamine (SP) in combination with azithromycin given at Antenatal Clinic, leads to lower rates of low birth weight deliveries (\<2.5 kg) among Papua New Guinean women, than the current standard treatment of SP and chloroquine.

Details

Lead sponsor	University of Melbourne
Phase	Phase 3
Status	COMPLETED
Enrolment	2793
Start date	2009-11
Completion	2013-01

Conditions

• Malaria in Pregnancy
• Sexually Transmitted Infections
• Anaemia

Interventions

• chloroquine, sulphadoxine pyrimethamine, LLIN
• azithromycin, sulphadoxine pyrimethamine, LLIN

Primary outcomes

• Proportion of women delivering low birth weight babies, <2500 g — At delivery

Countries

Papua New Guinea