NCT01120145 is a clinical trial in Malaria in Pregnancy, sponsored by Centers for Disease Control and Prevention.

Who is sponsoring NCT01120145?

NCT01120145 is sponsored by Centers for Disease Control and Prevention.

What condition does NCT01120145 study?

NCT01120145 studies Malaria in Pregnancy.

Is NCT01120145 still recruiting?

NCT01120145 is currently completed. Last updated 5 February 2013.

Last reviewed 2013-02-05 · How we verify

NCT01120145

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Assessment of the Efficacy and Effectiveness of Sulphadoxine-pyrimethamine for Intermittent Preventive Treatment of Malaria in Pregnancy in Malawi

Completed Last updated 5 February 2013

What this trial tests

trial in Malaria in Pregnancy in 1,410 participants. Completed in 1 January 2011.

Timeline

1 March 2010

Primary endpoint
1 January 2011

1 January 2011

Quick facts

Lead sponsor	Centers for Disease Control and Prevention
Status	Completed
Study type	OBSERVATIONAL
Enrollment	1,410
Start date	1 March 2010
Primary completion	1 January 2011
Estimated completion	1 January 2011
Sites	1 location across Malawi

Conditions studied

Malaria in Pregnancy — all drugs for Malaria in Pregnancy →

Sponsor

Centers for Disease Control and Prevention — full company profile →

Who can join

Eligibility, any sex, with Malaria in Pregnancy. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Therapeutic efficacy study: Development of fever or symptoms of severe malaria (defined by WHO) and parasitemia at any time after the first dose of SP during the 42 day follow up period
Time frame: 42 days
Birth outcomes study: Evidence of malaria infection based on placental histology at the time of delivery
Time frame: At time of birth
Characterizing molecular markers of SP resistance: Prevalence of molecular markers of sulphadoxine-pyrimethamine resistance at the time of health facility visit
Time frame: Day 1

Sponsor's own description

The purpose of this study is to determine the efficacy and effectiveness of sulphadoxine-pyrimethamine intermittent preventive treatment in pregnancy for reducing malaria-associated morbidity in pregnant women in Malawi.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

In vivo efficacy of sulphadoxine-pyrimethamine for the treatment of asymptomatic parasitaemia in pregnant women in Machinga District, Malawi.
Gutman J, Mwandama D, Wiegand RE, Abdallah J, et al · · 2015 · cited 8× · PMID 25962439 · DOI 10.1186/s12936-015-0710-7

Verify or expand the search:

Other recruiting trials for Malaria in Pregnancy

Currently open trials in the same condition.

NCT06529237 — Malaria Molecular Surveillance in Mozambique (Phase 2) · recruiting
NCT05426187 — Follow-up of Immunological Pattern and Pregnancy Outcomes in Women Previously Received Placental Malaria Vaccine · active not recruiting

Other Centers for Disease Control and Prevention trials

Trials by the same sponsor.

NCT06962904 — CDC-9 Inactivated Rotavirus Vaccine (IRV) Microneedle Patch (MNP) in Healthy Adults · Phase 1 · active not recruiting
NCT06485258 — CDC-9 Inactivated Rotavirus Vaccine (IRV) Intramuscular (IM) Phase 1 Clinical Trial in Healthy Adults · Phase 1 · completed
NCT05766267 — Short-course Regimens for the Treatment of Pulmonary Tuberculosis · Phase 2, PHASE3 · active not recruiting
NCT06045923 — Virologic and Immunologic Characteristics of Severe Mpox in Persons With Advanced HIV · recruiting
NCT06054269 — Clinical Trial to Evaluate the Immunogenicity of an Adjuvanted Influenza Vaccine Among HCP · Phase 3 · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01120145 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centers for Disease Control and Prevention
Last refreshed: 5 February 2013

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01120145.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing