Who is sponsoring NCT01114997?

NCT01114997 is sponsored by Cedars-Sinai Medical Center.

What condition does NCT01114997 study?

NCT01114997 studies Pain, Constipation, Nausea, Vomiting.

What drugs are being tested in NCT01114997?

Interventions: Lidocaine, Esmolol, Lidocaine + Esmolol (Combo).

What is the status of NCT01114997?

NCT01114997 is currently TERMINATED.

Last reviewed 2016-09-28 · How we verify

Effect of Lidocaine and Esmolol Alone or in Combination to Improve the Quality of Recovery, Maintaining Hemodynamic Stability During Abdominal Surgery

NCT01114997 Phase 4 TERMINATED Results posted

The purpose of this prospective, randomized, double-blinded, active-controlled study is: To assess the effectiveness of systemic administration of lidocaine and esmolol in combination (vs. either drug alone) will result in improved postoperative outcomes for patients undergoing abdominal surgery (e.g., less pain and postoperative constipation, nausea and vomiting, faster return of bowel function, resumption of normal activities of daily living), leading to a shorten length of hospital stay, maintaining hemodynamic stability during general anesthesia, when administered as intravenous adjuvants

Details

Lead sponsor	Cedars-Sinai Medical Center
Phase	Phase 4
Status	TERMINATED
Enrolment	32
Start date	2010-04
Completion	2015-06

Conditions

Pain
Constipation
Nausea
Vomiting

Interventions

Lidocaine
Esmolol
Lidocaine + Esmolol (Combo)

Primary outcomes

Post Operative Pain — 1 day
Outcome had a duration of one day at post-anesthesia care unit (PACU) Postoperative pain measured using a Verbal Rating Scale (VRS) Postoperative pain VRS scores: 0 = none pain to 10 = intolerable pain.
Number of Participants With Post Operative Pain One Month After Surgery — 1 month
Highest Post Operative pain one month after surgery, using a verbal rating score from 0 (no pain) to 10 (highest level of pain). Patient received a post-operative follow-up call one month after surgery.

Countries

United States