Who is sponsoring RECIA?

RECIA is sponsored by Northwestern University.

What condition does RECIA study?

RECIA studies Cervical Insufficiency.

What drugs are being tested in RECIA?

Interventions: Indomethacin and antibiotics (cefazolin or clindamycin).

Last reviewed 2014-11-05 · How we verify

Role in Emergent Cerclage of Indomethacin and Antibiotics (RECIA)

NCT01114516 NA COMPLETED Results posted

Though cervical insufficiency is a common cause of second trimester pregnancy loss, the placement of an emergent cerclage in these patients is thought to improve perinatal outcomes. It is unknown whether the use of tocolytics and antibiotics prolongs pregnancies complicated by need for emergent cerclage. The objective is to determine whether administration of peri-operative antibiotics and indomethacin to patients receiving emergent cerclages for cervical insufficiency increases latency period to delivery compared with patients receiving emergent cerclage alone.

Details

Lead sponsor	Northwestern University
Phase	NA
Status	COMPLETED
Enrolment	53
Start date	2010-03
Completion	2014-03

Conditions

Cervical Insufficiency

Interventions

Indomethacin and antibiotics (cefazolin or clindamycin)

Primary outcomes

Gestational Latency Achieved Between Cerclage Placement and Time of Delivery — 24 weeks
Median gestational latency achieved Between Cerclage Placement and Time of Delivery

Countries

United States