Last reviewed · How we verify
Prospective Randomized Controlled Clinical Study to Compare Tirofiban Intracoronary Bolus-Only vs Intravenous Bolus Plus Infusion in Patients With ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
The aim of this randomized trial is to compare the efficacy of high dose tirofiban administered as either an intracoronary bolus alone or as an intravenous bolus followed by a maintenance infusion with respect to microvascular perfusion and long term left ventricular infarct size, volumes and function.
Details
| Lead sponsor | Kosuyolu Heart Hospital |
|---|---|
| Phase | Phase 3 |
| Status | COMPLETED |
| Enrolment | 49 |
| Start date | 2008-09 |
| Completion | 2009-08 |
Conditions
- Acute Myocardial Infarction
Interventions
- tirofiban intracoronary bolus-only
- tirofiban intravenous bolus plus infusion
Primary outcomes
- Indices of microvascular perfusion — Post-PCI day 4 to 5
Intracoronary hemodynamic measures of index of microvascular resistance and coronary flow reserve