NCT01108874 is a Phase 2 clinical trial of Metaraminol in Hypotension, sponsored by Federal University of São Paulo.

Who is sponsoring NCT01108874?

NCT01108874 is sponsored by Federal University of São Paulo.

What drugs are being tested in NCT01108874?

Interventions in NCT01108874: Metaraminol.

What condition does NCT01108874 study?

NCT01108874 studies Hypotension.

Is NCT01108874 still recruiting?

NCT01108874 is currently completed. Last updated 30 September 2010.

Last reviewed 2010-09-30 · How we verify

NCT01108874

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Up-Down Determination of the ED90 of Metaraminol to Treat Hypotension During Elective Cesarean Section

Completed Phase 2 Last updated 30 September 2010

What this trial tests

Phase 2 trial testing Metaraminol in Hypotension in 48 participants. Completed in 1 August 2010.

Timeline

1 November 2009

Primary endpoint
1 August 2010

1 August 2010

Quick facts

Lead sponsor	Federal University of São Paulo
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	single group
Masking	triple
Primary purpose	treatment
Enrollment	48
Start date	1 November 2009
Primary completion	1 August 2010
Estimated completion	1 August 2010
Sites	1 location across Brazil

Drugs / interventions tested

Metaraminol (METARAMINOL) — full drug profile →

Conditions studied

Hypotension — all drugs for Hypotension →

Sponsor

Federal University of São Paulo

Who can join

18 and older, female only, with Hypotension. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

The ED90 of Metaraminol to treat hypotension in elective cesarean section will be determined.
Time frame: From spinal induction until delivery (on average 30-60min)
Bolus doses of metaraminol will be used every time SBP falls below baseline values and maternal responses to doses will be used to build a dose response curve from where ED90 will be estimated.

Sponsor's own description

The purpose of this study is to find the best dose of metaraminol to be used in patients during elective cesarean sections.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Hypotension

Currently open trials in the same condition.

NCT07499947 — Predicting Spinal Hypotension in Cesarean Section · recruiting
NCT07494955 — "Effect of Pre-Spinal Mindfulness-Based Breathing Exercise on Hemodynamic Response in Elective Cesarean Section" · NA · recruiting
NCT07481851 — Skin Conductance for Predicting Spinal Anesthesia-Induced Hypotension in Geriatric Urologic Oncology Patients · recruiting
NCT06994494 — Noninvasive Continuous BP Monitoring in Newborns Based on Pulsatile Signal Morphological Features Using NIRS · recruiting
NCT06953193 — Intraoperative Hypotension in Pancreatoduodenectomy: A Randomized Trial of General Versus Combined Anesthesia · NA · recruiting

Other Federal University of São Paulo trials

Trials by the same sponsor.

NCT07376811 — Effect Of Sleeping Posture Guidance On Sleep Quality In Patients With Rotator Cuff Syndrome · NA · not yet recruiting
NCT06805656 — Multi Interventional Approaches to Mitigate HIV Reservoirs Aiming the Sustained HIV Remission Without Antiretrovirals · Phase 2 · not yet recruiting
NCT06970964 — Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before a · NA · completed
NCT06905860 — Intra-articular Infiltration of Platelet-Rich Fibrin vs Corticosteroid in Mild to Moderate Knee Osteoarthritis · Phase 4 · not yet recruiting
NCT06829992 — Effects of Applying Kinesio Tapping on Primary Dysmenorrhea in Football Players · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01108874 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Federal University of São Paulo
Last refreshed: 30 September 2010

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01108874.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing