NCT01090882 is a NA clinical trial of Bupivocaine in Gall Stones, sponsored by University Hospitals Coventry and Warwickshire NHS Trust.

Who is sponsoring NCT01090882?

NCT01090882 is sponsored by University Hospitals Coventry and Warwickshire NHS Trust.

What drugs are being tested in NCT01090882?

Interventions in NCT01090882: Bupivocaine, 0.9% normal saline solution.

What condition does NCT01090882 study?

NCT01090882 studies Gall Stones.

Is NCT01090882 still recruiting?

NCT01090882 is currently completed. Last updated 17 June 2024.

Last reviewed 2024-06-17 · How we verify

NCT01090882

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Efficacy of Intraperitoneal Local Anaesthetic Techniques During Laparoscopic Cholecystectomy: A Double Blind Randomized Controlled Trial

Completed NA Last updated 17 June 2024

What this trial tests

NA trial testing Bupivocaine in Gall Stones in 128 participants. Completed in 1 October 2009.

Timeline

1 July 2009

Primary endpoint
1 October 2009

1 October 2009

Quick facts

Lead sponsor	University Hospitals Coventry and Warwickshire NHS Trust
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	factorial
Masking	quadruple
Primary purpose	treatment
Enrollment	128
Start date	1 July 2009
Primary completion	1 October 2009
Estimated completion	1 October 2009
Sites	1 location across United Kingdom

Drugs / interventions tested

Bupivocaine — full drug profile →
0.9% normal saline solution

Conditions studied

Gall Stones — all drugs for Gall Stones →

Sponsor

University Hospitals Coventry and Warwickshire NHS Trust

Who can join

18 and older, any sex, with Gall Stones. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

VAS pain score
Time frame: 1, 4, 8 hours after operation and at discharge

Sponsor's own description

Pain following laparoscopic cholecystectomy (LC) results in morbidity and is a barrier to same day discharge. In several trials local anaesthetic (LA) washed over the liver and gall bladder decreases pain. In many patients pain has a strong component attributable to diaphragmatic origin. A wash of LA over the liver and gall bladder is unlikely to provide high levels of analgesia to pain fibres from the diaphragm. The investigators hypothesise that LA injected to the right hemidiaphragm during LC would be more effective than wash. Methods Double blind randomised controlled trial of 128 consecutive subjects undergoing elective LC. Control -sham injection of diaphragm and sham wash over liver/GB with saline; Test treatment 'subperitoneal LA' - bupivocaine injection/sham wash; Internal control 'topical LA' - sham injection/bupivocaine wash. Primary outcome: pain scores in theatre recovery and the ward. Secondary outcomes: analgesic use, physiological observations, time to eating and mobilising, day case surgery.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other University Hospitals Coventry and Warwickshire NHS Trust trials

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT01090882 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospitals Coventry and Warwickshire NHS Trust
Last refreshed: 17 June 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT01090882.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing