Comparison Between Dexchlorpheniramine and Dexchlorpheniramine/Pseudoephedrine/Guaifenesin in the Relief of Allergic Symptoms in Rhinitic Patients With Viral Upper Respiratory Tract Infections and Productive Cough

NCT01085721 Phase 3 UNKNOWN

Patients with allergic rhinitis frequently present exacerbation of the atopic symptoms during viral infections of the upper respiratory tract. Also, allergic rhinitis makes the mucosa more reactive to infectious agents and potentiates mucus production. The combination of dexchlorpheniramine, pseudoephedrine and guaifenesin elicits antihistaminic, decongestant and expectorant effects. The study hypothesizes is that this product is superior to dexchlorpheniramine alone in the relief of allergic symptoms and in promoting mucus elimination in atopic patients with viral infections of the upper respiratory tract.

Details

Lead sponsor	Mantecorp Industria Quimica e Farmaceutica Ltd.
Phase	Phase 3
Status	UNKNOWN
Enrolment	170

Conditions

• Viral Infections of the Upper Respiratory Tract

Interventions

• Dexchlorpheniramine, pseudoephedrine, guaifenesin
• Dexchlorpheniramine

Primary outcomes

• Symptoms frequency and intensity evaluated with a 5 point visual analogic scale (VAS) — 5 days