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The Influence of Furosemide on Fluid Balance and Intra-abdominal Pressure in Mechanically Ventilated Critically Ill Patients With Secondary Intra-abdominal Hypertension
Intra-abdominal hypertension (IAH) is a frequent cause of organ dysfunction in critically ill patients. Secondary IAH is mainly caused by excessive fluid resuscitation.The World Society for the Abdominal Compartment Syndrome (WSACS) recommends using diuretics to remove excess fluids and decrease intra-abdominal pressure (IAP). However, critically ill patients may not tolerate negative fluid balance in the acute phase of their disease and the injured kidney may not respond to diuretics. The aim of this study is to evaluate the influence of furosemide on fluid balance, IAP and kidney function in critically ill patients.
Details
| Lead sponsor | Ziekenhuis Netwerk Antwerpen (ZNA) |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 30 |
| Start date | 2010-02 |
| Completion | 2012-03 |
Conditions
- Intra-Abdominal Hypertension
Interventions
- furosemide
Primary outcomes
- intra-abdominal pressure — every 4 hours during furosemide administration and daily for 7 days
Countries
Belgium