Open-label, Randomized Clinical Trial in Kenya to Determine the Effectiveness of Artesunate + Sulfamethoxypyrazine/Pyrimethamine Vs. Praziquantel in the Treatment of S. Mansoni in Children

NCT01054651 Phase 3 COMPLETED

The purpose of this study is to determine the comparative efficacy of artesunate plus sulfamethoxypyrazine-pyrimethamine versus Praziquantel in the treatment of school children infected with S.mansoni in western Kenya.

Details

Lead sponsor	Kenya Medical Research Institute
Phase	Phase 3
Status	COMPLETED
Enrolment	212
Start date	2009-10
Completion	2009-12

Conditions

• Schistosoma Mansoni

Interventions

• Artesunate+Sulfamethoxypyrazine/pyrimethamine
• Praziquantel

Primary outcomes

• Compare the cure rate between the two treatment arms — after 28 days

Countries

Kenya