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NCT01035723

Effect of Functional Genetic Polymorphisms on Brain Morphology and Function

Completed Last updated 16 December 2019
What this trial tests

trial in Drug Abuse in 221 participants. Completed in 25 February 2013.

Timeline
13 September 2005
25 February 2013

Quick facts

Lead sponsorNational Institute on Drug Abuse (NIDA)
StatusCompleted
Study typeOBSERVATIONAL
Enrollment221
Start date13 September 2005
Estimated completion25 February 2013
Sites1 location across United States

Conditions studied

Sponsor

National Institute on Drug Abuse (NIDA)

Who can join

Adults 18 to 50, any sex, with Drug Abuse. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: \- New research on genetics and the human genome has helped to identify certain genes that affect specific parts of the brain, including the parts that may be involved in drug use and dependency. Researchers are interested in studying both genetic information and brain activity to better understand variations in brain function among individuals. Objectives: \- To study brain activity in conjunction with specific genetic information provided by healthy volunteers including smokers, non-smokers, people with drug dependence, and those who do not have any dependence on any substance. Eligibility: \- Healthy volunteers between 18 and 50 years of age. Design: * This is an 8 10 hour study which may be completed in 1, 2, or 3 visits. * Participants will complete questionnaires about emotional and psychological responses to different situations, including stressful situations. * Participants will have a training session in a mock (fake) scanner to practice tasks to be completed in the real scanner. * Participants will have the following two types of magnetic resonance imaging (MRI) scans in one scan session of the brain: * A structural MRI scan to provide basic information about each participant's brain. * A functional MRI scanning session, in which participants will perform a memory task to provide information about brain activity. * Participants will provide blood samples for research and testing....

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other recruiting trials for Drug Abuse

Currently open trials in the same condition.

Other National Institute on Drug Abuse (NIDA) trials

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Data sources for this page

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