Last reviewed · How we verify
Prolonging Remission in Depressed Elderly (PRIDE)
This study will determine whether medications alone or medications and electroconvulsive therapy (ECT) work best to prevent depressive relapse and to improve quality of life for older people with severe mood disorders.
Details
| Lead sponsor | Icahn School of Medicine at Mount Sinai |
|---|---|
| Phase | Phase 4 |
| Status | COMPLETED |
| Enrolment | 247 |
| Start date | 2010-01 |
| Completion | 2016-03 |
Conditions
- Depression
Interventions
- lithium and Venlafaxine
- ECT
Primary outcomes
- Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) — Measured at every week
Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) Measured at clinic visits at baseline and weeks 2, 4, 6, 8, 10,12,14,16, 18, 20, 22, 24. Measured by a telephone interview at weeks 5, 7, 9, 11, 13, 15, 17, 19, 21, 23 - Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) — Measured at clinic visits at week 2
Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) Measured at clinic visits at baseline and weeks 2, 4, 6, 8, 10,12,14,16, 18, 20, 22, 24. Measured by a telephone interview at weeks 5, 7, 9, 11, 13, 15, 17, 19, 21, 23 - Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) — Measured at clinic visits at week 4
Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) Measured at clinic visits at baseline and weeks 2, 4, 6, 8, 10,12,14,16, 18, 20, 22, 24. Measured by a telephone interview at weeks 5, 7, 9, 11, 13, 15, 17, 19, 21, 23 - Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) — Measured by a telephone interview at week 5
Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) Measured at clinic visits at baseline and weeks 2, 4, 6, 8, 10,12,14,16, 18, 20, 22, 24. Measured by a telephone interview at weeks 5, 7, 9, 11, 13, 15, 17, 19, 21, 23 - Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) — Measured at clinic visits at week 6
Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) Measured at clinic visits at baseline and weeks 2, 4, 6, 8, 10,12,14,16, 18, 20, 22, 24. Measured by a telephone interview at weeks 5, 7, 9, 11, 13, 15, 17, 19, 21, 23 - Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) — Measured by a telephone interview at week 7
Long-term antidepressant efficacy (Hamilton Rating Scale for Depression) Measured at clinic visits at baseline and weeks 2, 4, 6, 8, 10,12,14,16, 18, 20, 22, 24. Measured by a telephone interview at weeks 5, 7, 9, 11, 13, 15, 17, 19, 21, 23
Countries
United States