Efficacy of a Bolus Dose of Remifentanil Compared to a Bolus Dose of Intravenous lidocaïne on the Incidence of Coughing During Emergence of Anesthesia.

NCT01026129 NA COMPLETED

This study is designed to compare the effects of a bolus dose of remifentanil to a bolus dose of lidocaine given prior to the emergence of anesthesia: * on the incidence of perioperative coughing * on the time needed for the emergence of a desflurane-based anesthesia * on the incidence of sore throat after extubation. Our hypothesis is that the use of a remifentanil bolus dose given prior to emergence of a desflurane-based anesthesia will reduce the incidence of perioperative coughing from 70% to 35% compared to lidocaine.

Details

Lead sponsor	Centre hospitalier de l'Université de Montréal (CHUM)
Phase	NA
Status	COMPLETED
Enrolment	93
Start date	2010-04
Completion	2010-07

Conditions

• Cough
• Anesthesia
• Extubation

Interventions

• Remifentanil
• Remifentanil
• lidocaine

Primary outcomes

• Incidence of coughing during emergence and the first ten minutes after extubation. — From emergence until 10 minutes after extubation

Countries

Canada