Short and Long Term Efficacy of Combined Treatment in Controlling IGI-I Levels in Acromegaly

NCT01014793 COMPLETED

In acromegaly, nearly 40% of patients fail to control GH/IGF-I levels with somatostatin analogues (SA). Dopaminergic agonists (DA) are even less effective, but combination therapy with SA and DA normalizes IGF-I levels in 33-56% of patients in short-term studies. This study was designed to evaluate short and long term efficacy of cabergoline in controlling IGF-I levels in acromegalic patients receiving octreotide.

Details

Lead sponsor	Federal University of São Paulo
Status	COMPLETED
Enrolment	19
Start date	2005-05
Completion	2008-12

Conditions

• Acromegaly

Interventions

• cabergoline

Primary outcomes

• Control of IGF-I levels — six months

Countries

Brazil