Who is sponsoring NICOREN?

NICOREN is sponsored by Centre Hospitalier Universitaire, Amiens.

What condition does NICOREN study?

NICOREN studies Chronic Renal Failure, Hemodialysis.

What drugs are being tested in NICOREN?

Interventions: nicotinamide, sevelamer, cinacalcet.

What is the status of NICOREN?

NICOREN is currently TERMINATED.

Last reviewed 2016-05-13 · How we verify

Comparison of Nicotinamide and Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients (NICOREN)

NCT01011699 Phase 3 TERMINATED

The comparison between nicotinamide and sevelamer aims to demonstrate, in chronic hemodialysed patients, the non-inferiority of nicotinamide in terms of control of the phosphatemia. Secondary objectives is to compare the two treatments in terms of efficiency in other biological parameters, vascular calcification and bone mass loss and on the clinical and biological tolerance and finally to explore the roles of metabolites of nicotinamide.

Details

Lead sponsor	Centre Hospitalier Universitaire, Amiens
Phase	Phase 3
Status	TERMINATED
Enrolment	176
Start date	2010-01
Completion	2013-06

Conditions

Chronic Renal Failure
Hemodialysis

Interventions

nicotinamide
sevelamer
cinacalcet

Primary outcomes

The comparison between nicotinamide and Sevelamer was primarily to demonstrate the noninferiority of nicotinamide in terms of control of the phosphatemia observed during the 4th, 5th and 6th months before to introduce Cinacalcet ®. — 6th months

Countries

France