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Methods to Augment the Efficacy of Aspirin and Clopidogrel in Healthy Subjects (ASA Only) and Patients With Stable Coronary Artery Disease (Taking Clopidogrel Only) or (Taking Clopidogrel & ASA) With an Elevated Platelet Turnover (Reticulated Platelets). (Dual-Dosing)
The investigators will test the hypothesis that aspirin or clopidogrel taken twice daily will augment their antiplatelet efficacy in patients with an elevated platelet turnover (as measured by the proportion of reticulated (young) platelets) compared with once daily dosing.
Details
| Lead sponsor | Neil Kleiman, MD |
|---|---|
| Phase | Phase 4 |
| Status | WITHDRAWN |
| Start date | 2009-09 |
| Completion | 2011-09 |
Conditions
- Coronary Artery Disease
Interventions
- Asprin
- Clopidogrel
Primary outcomes
- To look if dual dosing of aspirin and/or clopidogrel will augment antiplatelet efficacy in patients with elevated reticulated platelet turnover. — 1 year
Countries
United States