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NCT00992147

A Phase II/III Clinical Study of ANTG-adip for the Treatment of Depressed Scar to Evaluate Safety and Efficacy

Completed Phase 2/Phase 3 Last updated 8 October 2009
What this trial tests

Phase 2/Phase 3 trial testing Adipocell in Depressed Scar in 36 participants. Completed in 1 March 2007.

Timeline
1 May 2004
1 March 2007

Quick facts

Lead sponsorAnterogen Co., Ltd.
PhasePhase 2/Phase 3
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment36
Start date1 May 2004
Estimated completion1 March 2007
Sites1 location across South Korea

Drugs / interventions tested

Conditions studied

Sponsor

Anterogen Co., Ltd. — full company profile →

Who can join

19 and older, any sex, with Depressed Scar. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Sponsor's own description

Autologous cultured adipocytes (ANTG-adip) is produced by well-established techniques including cell harvesting from lipoaspirates, expansion of adipose tissue derived stem cells, and differentiation into pure and immature adipocytes. This was an open-label, dose-escalation study. Patients are given subcutaneous injection of ANTG-adip and followed for 12 weeks according to the clinical trial protocol.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications.
    Dai R, Wang Z, Samanipour R, Koo KI, et al · · 2016 · cited 191× · PMID 27057174 · DOI 10.1155/2016/6737345
  2. Adipose-derived stromal cells: Their identity and uses in clinical trials, an update.
    Casteilla L, Planat-Benard V, Laharrague P, Cousin B. · · 2011 · cited 162× · PMID 21607134 · DOI 10.4252/wjsc.v3.i4.25
  3. Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging.
    Gaur M, Dobke M, Lunyak VV. · · 2017 · cited 105× · PMID 28117680 · DOI 10.3390/ijms18010208

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Other Anterogen Co., Ltd. trials

Trials by the same sponsor.

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Data sources for this page

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