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NCT00992147
A Phase II/III Clinical Study of ANTG-adip for the Treatment of Depressed Scar to Evaluate Safety and Efficacy
Phase 2/Phase 3 trial testing Adipocell in Depressed Scar in 36 participants. Completed in 1 March 2007.
Quick facts
| Lead sponsor | Anterogen Co., Ltd. |
|---|---|
| Phase | Phase 2/Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 36 |
| Start date | 1 May 2004 |
| Estimated completion | 1 March 2007 |
| Sites | 1 location across South Korea |
Drugs / interventions tested
- Adipocell — full drug profile →
Conditions studied
- Depressed Scar — all drugs for Depressed Scar →
Sponsor
Anterogen Co., Ltd. — full company profile →
Who can join
19 and older, any sex, with Depressed Scar. Patients with the condition only — healthy volunteers not accepted.
What's being measured
Primary outcomes are the specific endpoints the trial is designed to prove or disprove.
-
Efficacy: recovery rate(%)
Time frame: week 12 - Safety: clinically measured abnormality of laboratory tests and adverse events, Injection site observation, Immune rejection test
Sponsor's own description
Autologous cultured adipocytes (ANTG-adip) is produced by well-established techniques including cell harvesting from lipoaspirates, expansion of adipose tissue derived stem cells, and differentiation into pure and immature adipocytes. This was an open-label, dose-escalation study. Patients are given subcutaneous injection of ANTG-adip and followed for 12 weeks according to the clinical trial protocol.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
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Adipose-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Applications.
Dai R, Wang Z, Samanipour R, Koo KI, et al · · 2016 · cited 191× · PMID 27057174 · DOI 10.1155/2016/6737345 -
Adipose-derived stromal cells: Their identity and uses in clinical trials, an update.
Casteilla L, Planat-Benard V, Laharrague P, Cousin B. · · 2011 · cited 162× · PMID 21607134 · DOI 10.4252/wjsc.v3.i4.25 -
Mesenchymal Stem Cells from Adipose Tissue in Clinical Applications for Dermatological Indications and Skin Aging.
Gaur M, Dobke M, Lunyak VV. · · 2017 · cited 105× · PMID 28117680 · DOI 10.3390/ijms18010208
Verify or expand the search:
- PubMed search for NCT00992147
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Anterogen Co., Ltd. trials
Trials by the same sponsor.
- NCT06539429 — Clinical Study to Evaluate Efficacy and Safety of ANT-301 in Patients With Knee Osteoarthritis in Grade III/IV by K/L · Phase 1 · active not recruiting
- NCT05157958 — Study to Evaluate Safety and Efficacy of ALLO-ASC-SHEET in Subjects With Dystrophic Epidermolysis Bullosa · Phase 2 · recruiting
- NCT06141811 — A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-302 Clinical Trial · recruiting
- NCT04569409 — Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Wagner Grade 2 Foot Ulcers. · Phase 3 · completed
- NCT04590703 — A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-301 Clinical Trial · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT00992147 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Anterogen Co., Ltd.
- Last refreshed: 8 October 2009
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00992147.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing