Phase 4 Study of Helicobacter Pylori Eradication Therapy

NCT00990405 Phase 4 UNKNOWN

The role of Helicobacter pylori infection in functional dyspepsia remains controversial. Several randomized controlled trials in western countries have shown no significant advantage over placebo. But some recent studies in Asian population were different compared to the result of studies in the Western population. At the present time, it seems to be difficult to conclude the efficacy of the H.pylori eradication therapy in patients with H. pylori-infected functional dyspepsia. The investigators hypothesize that eradication of Helicobacter pylori has a sustained global symptom improvement in patients with H. pylori infected functional dyspepsia.

Details

Lead sponsor	Korean College of Helicobacter and Upper Gastrointestinal Research
Phase	Phase 4
Status	UNKNOWN
Enrolment	400
Start date	2009-10
Completion	2010-12

Conditions

• Functional Dyspepsia
• Helicobacter Pylori Infection

Interventions

• Lansoprzole+Amoxicillin+Clarithromycin

Primary outcomes

• Global symptom improvement after eradication of Helicobacter pylori in patients with functional dyspepsia therapy) — Symptom assessment at 8 weeks after eradication

Countries

South Korea