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Tumescent Lidocaine Bioavailability and Absorption Kinetics:Maximum Safe mg/kg Lidocaine Dosage (TLA)
This pharmacokinetic clinical trial is a dose ranging study of lidocaine in tumescent local anesthesia. The goal is to understand the absorption pharmacokinetic of tumescent lidocaine and to determine an objective (statistical) estimate of the maximum safe mg/kg dosage of lidocaine in tumescent local anesthesia without liposuction.
Details
| Lead sponsor | Klein, Jeffrey A., M.D. |
|---|---|
| Phase | Phase 1/Phase 2 |
| Status | UNKNOWN |
| Enrolment | 14 |
| Start date | 2005-01 |
| Completion | 2011-08 |
Conditions
- Anesthesia
Interventions
- Tumescent Local Anesthesia (lidocaine, epinephrine)
- Liposuction
Primary outcomes
- Peak or maximum serum lidocaine concentration (Cmax) following a given mg/kg dosage of lidocaine delivered by subcutaneous infiltration of tumescent local anesthesia — 24 hours
Countries
United States