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Use of the Medicinal Mushroom Agaricus Blazei Murill in Addition to High Dose Chemotherapy in Patients With Multiple Myeloma.
Extract from the mushroom Agaricus blazei Murill har been shown to have strong immunomodulating properties both in cell cultures, animal models and in humans. Furthermore antitumor properties have been shown in animal models, among them in mice with multiple myeloma. The investigators now want to investigate the effect of Agaricus as supplementary treatment in addition to chemotherapy in patients with multiple myeloma.
Details
| Lead sponsor | Ullevaal University Hospital |
|---|---|
| Phase | Phase 2 |
| Status | COMPLETED |
| Enrolment | 39 |
| Start date | 2009-06 |
| Completion | 2014-02 |
Conditions
- Multiple Myeloma
Interventions
- Intake of 60 ml placebo daily in addition to chemotherapy
- Intake of 60 ml agaricus daily in addition to chemotherapy
Primary outcomes
- Cytokine levels in serum — 7 weeks
Countries
Norway