NCT00966953 is a Phase 3 clinical trial of Fluoride in Gingival Diseases, sponsored by Colgate Palmolive.

Who is sponsoring NCT00966953?

NCT00966953 is sponsored by Colgate Palmolive.

What drugs are being tested in NCT00966953?

Interventions in NCT00966953: Fluoride, Triclosan/Fluoride toothpaste, Fluoride, Fluoride, antibacterial plant extract.

What condition does NCT00966953 study?

NCT00966953 studies Gingival Diseases.

Is NCT00966953 still recruiting?

NCT00966953 is currently completed. Last updated 14 September 2009.

Are results published for NCT00966953?

Yes — primary outcome results have been posted to ClinicalTrials.gov. See the outcomes section above for details.

Last reviewed 2009-09-14 · How we verify

NCT00966953

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.

Completed Phase 3 Results posted Last updated 14 September 2009

What this trial tests

Phase 3 trial testing Fluoride in Gingival Diseases in 25 participants. Completed in 1 January 2008.

Timeline

1 October 2007

Primary endpoint
1 January 2008

1 January 2008

Quick facts

Lead sponsor	Colgate Palmolive
Phase	Phase 3
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	25
Start date	1 October 2007
Primary completion	1 January 2008
Estimated completion	1 January 2008
Sites	1 location across United States

Drugs / interventions tested

Fluoride — full drug profile →
Triclosan/Fluoride toothpaste — full drug profile →
Fluoride — full drug profile →
Fluoride — full drug profile →
antibacterial plant extract

Conditions studied

Gingival Diseases — all drugs for Gingival Diseases →

Sponsor

Colgate Palmolive — full company profile →

Who can join

Adults 18 to 65, any sex, with Gingival Diseases. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Plaque Index
Time frame: 8 weeks
Plaque score scale: Units on a scale 0 to 5 (0 = no plaque, 1 = separate flecks of plaque on the tooth, 2 = a thin continuous band of plaque, 3 = a band of plaque up to one-third of the tooth, 4 = plaque covering up to two thirds of the of the tooth, 5 = plaque covering two-thirds or more of the crown of the tooth)

Sponsor's own description

Clinical research study to determine the anti-plaque efficacy of prototype dentifrices via a 4-day brushing regiment

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of Fluoride

Trials testing the same drug.

NCT06362681 — Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study · NA · recruiting
NCT06202495 — Dentine Hypersensitivity Treated With Laser and Fluoride. · NA · unknown
NCT05600517 — Evaluation of Caries Prevention Based on Genetic Etiology and Risk. · NA · unknown
NCT02357979 — Fissure Caries Inhibition Study With Solea CO2-9.3μm Short-pulsed Laser · NA · completed
NCT05810389 — EVALUATION OF AN ALTERNATIVE TECHNIQUE FOR THE APPLICATION OF SODIUM FLUOROPHOSPHATE: A 2-YEARS DOUBLE-BLIND RCT · Phase 4 · completed

Other recruiting trials for Gingival Diseases

Currently open trials in the same condition.

NCT07104019 — Biofiller and Gingival Phenotype Thickening · NA · recruiting
NCT06490679 — Evaluation Of Nonsurgical Treatment Of Deep Periodontal Pockets (7-10mm) Using AIRFLOW® Prophylaxis Master Device With E · NA · recruiting
NCT06351982 — Treatment Of Shallow Periodontal Pockets 4-6mm Using AIRFLOW Prophylaxis Master Device With Erythritol vs Manual Scalers · NA · recruiting
NCT05759780 — OCT Vibrography for Biomechanical Properties of Tissues · NA · recruiting
NCT07536204 — Characterization of JAK1 and JAK2 Activation in Gingival Tissues During Homeostasis and Periodontitis · recruiting

Other Colgate Palmolive trials

Trials by the same sponsor.

NCT07398846 — Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reduci · Phase 3 · recruiting
NCT07276672 — Efficacy of a Toothpaste Containing Hydrogen Peroxide as Compared to a Regular Fluoride Toothpaste Without Hydrogen Pero · Phase 3 · completed
NCT07225478 — Clinical Study to Evaluate the Tooth Whitening Efficacy of a New NextGen In-office Whitening System · Phase 3 · completed
NCT07224828 — The Efficacy of a Battery Toothbrush in the Reduction of Established Plaque and Gingivitis · Phase 3 · completed
NCT07134231 — Clinical Study to Evaluate the Anti-cavity Efficacy of Three Dentifrices: An In Situ Model · Phase 3 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00966953 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Colgate Palmolive
Last refreshed: 14 September 2009

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00966953.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing