Who is sponsoring MRI-AF?

MRI-AF is sponsored by Mayo Clinic.

What condition does MRI-AF study?

MRI-AF studies Atrial Fibrillation.

What drugs are being tested in MRI-AF?

Interventions: mangosteen juice, placebo juice.

What is the status of MRI-AF?

MRI-AF is currently TERMINATED.

Last reviewed 2016-03-14 · How we verify

Mangosteen Effects on Inflammatory Markers in Atrial Fibrillation Trial (MRI-AF)

NCT00951301 Phase 1 TERMINATED

This study is being done to see if the addition of mangosteen juice to standard medical care will reduce the risk of atrial fibrillation (AF) recurrence following direct current (DC) cardioversion. The study will also look at the effects the mangosteen juice may have on biomarkers of inflammation and endothelial cell dysfunction (the tissue lining the arteries does not function properly).

Details

Lead sponsor	Mayo Clinic
Phase	Phase 1
Status	TERMINATED
Enrolment	143
Start date	2009-07
Completion	2013-06

Conditions

Atrial Fibrillation

Interventions

mangosteen juice
placebo juice

Primary outcomes

Test the hypothesis that the addition of mangosteen juice as a dietary supplement may reduce the measured levels of inflammatory biomarkers interleukin 1, interleukin 6, C-reactive protein (CRP), and tumor necrosis factor alpha (TNF a) etc). — 6 months

Countries

United States