Combining Varenicline and Bupropion for Smoking Cessation

NCT00943618 PHASE3 COMPLETED Results posted

The goal of this clinical research study is learn if the combination of Chantix (varenicline) and Zyban (bupropion) is more effective at helping people to quit smoking than varenicline when given alone. Researchers also want to learn if this drug combination can reduce cravings and other negative symptoms of nicotine withdrawal better than varenicline does alone. The safety of this drug combination will also be tested.

Details

Lead sponsor	M.D. Anderson Cancer Center
Phase	PHASE3
Status	COMPLETED
Enrolment	641
Start date	Mon May 17 2010 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Thu Sep 09 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Smoking Cessation

Interventions

• Varenicline
• Bupropion
• Placebo
• Counseling/Phone Calls

Countries

United States