Who is sponsoring NCT00941174?

NCT00941174 is sponsored by The Hospital for Sick Children.

What drugs are being tested in NCT00941174?

Interventions: 13C5-Calcium-L-Leucovorin.

What is the status of NCT00941174?

NCT00941174 is currently COMPLETED.

Last reviewed 2013-12-30 · How we verify

Folate Absorption Across the Large Intestine, Study #2: Capsule Study

NCT00941174 Phase 1 COMPLETED

The objective of this study is to determine whether the intact human colon with an unaltered microflora distribution absorbs folate and to what extent it is absorbed into the systemic circulation using a dual/oral intravenous route. This will elicit an understanding of colonic folate absorption and metabolism.

Details

Lead sponsor	The Hospital for Sick Children
Phase	Phase 1
Status	COMPLETED
Enrolment	9
Start date	2008-09
Completion	2009-03

Conditions

Healthy

Interventions

13C5-Calcium-L-Leucovorin

Primary outcomes

Blood Folate - Study Period 1 — Day 1 (Baseline), Day 2 (0h,1h,2h,3h,4h,5h,6h,7h,8h,9h,10h,11h,12h,24hr,48hr)
Blood Folate - Study Period 2 — Day 2 (0h, 0.25h,0.5h,1h,1.5h,2h,2.5h,3h,3.5h,4h)
Urine Folate - Study Period 1 — 24h, 48h, 72h, 96h
Urine Folate - Study Period 2 — 24h, 48h, 72h

Countries

Canada