Who is sponsoring NCT00939133?

NCT00939133 is sponsored by Dermatrials Research.

What drugs are being tested in NCT00939133?

Interventions: tretinoin microsphere 0.04% gel, vehicle gel.

What is the status of NCT00939133?

NCT00939133 is currently COMPLETED.

Last reviewed 2015-02-09 · How we verify

Double Blinded Vehicle Controlled Proof of Concept Study to Investigate the Recurrence of Inflammatory and Non-inflammatory Acne Lesions Using Tretinoin Gel (Microsphere) 0.04% in Male Patients Post Oral Isotretinoin Use

NCT00939133 Phase 4 COMPLETED

The use of topical retinoids is a mainstay and basis of early acne treatment to prevent the progression to inflammatory lesions. Post oral isotretinoin, it is not uncommon for non-inflammatory papules and comedones to recur. However, there has been no formal study to look at the prevention of recurrence of these acne lesions post isotretinoin in a long term basis. This may enhance the therapeutic options for post isotretinoin patients in order to prevent recurrence of their disease. Hypothesis Tretinoin microsphere 0.04% will prevent recurrence of acne lesions.

Details

Lead sponsor	Dermatrials Research
Phase	Phase 4
Status	COMPLETED
Enrolment	20
Start date	2009-07
Completion	2010-12

Conditions

Acne

Interventions

tretinoin microsphere 0.04% gel
vehicle gel

Primary outcomes

Primary objectives-to assess the efficacy of Retin A micro 0.04% on the recurrence rate of acne post isotretinoin use compared to vehicle. — Six Months

Countries

Canada