Last reviewed · How we verify
An Open-label, Three-treatment, Three-period, One-sequence, Crossover Study to Evaluate the Effect of Ketoconazole and Rifampicin on the Pharmacokinetics of Fimasartan in Healthy Male Volunteers
To evaluate the effect of ketoconazole and rifampicin on the pharmacokinetics of fimasartan.
Details
| Lead sponsor | Boryung Pharmaceutical Co., Ltd |
|---|---|
| Phase | Phase 1 |
| Status | COMPLETED |
| Enrolment | 24 |
| Start date | 2009-04 |
| Completion | 2009-08 |
Conditions
- Essential Hypertension
Interventions
- Fimasartan, Ketoconazole, Rifampicin
Primary outcomes
- Cmax, AUClast, AUCinf, CL/F, Tmax, t1/2 — 0, 0.5, 1, 1.5, 2, 2.5, 3, 4, 6, 8, 12, 24, 32, (48, 56) h