NCT00937807 is a Phase 4 clinical trial of xenon in Hemodynamic Stability, sponsored by Air Liquide Santé International.

Who is sponsoring NCT00937807?

NCT00937807 is sponsored by Air Liquide Santé International.

What drugs are being tested in NCT00937807?

Interventions in NCT00937807: xenon, sévoflurane.

What condition does NCT00937807 study?

NCT00937807 studies Hemodynamic Stability.

Is NCT00937807 still recruiting?

NCT00937807 is currently completed. Last updated 10 September 2025.

Last reviewed 2025-09-10 · How we verify

NCT00937807

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Hemodynamic Stability During Carotid Endarterectomy Under General Anesthesia in Elderly Patients: Comparison LENOXe™ (xénon 100% v/v) Versus SEVOFLURANE

Completed Phase 4 Last updated 10 September 2025

What this trial tests

Phase 4 trial testing xenon in Hemodynamic Stability in 84 participants. Completed in 1 April 2010.

Timeline

1 July 2009

Primary endpoint
1 February 2010

1 April 2010

Quick facts

Lead sponsor	Air Liquide Santé International
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	84
Start date	1 July 2009
Primary completion	1 February 2010
Estimated completion	1 April 2010
Sites	1 location across France

Drugs / interventions tested

xenon — full drug profile →
sévoflurane — full drug profile →

Conditions studied

Hemodynamic Stability — all drugs for Hemodynamic Stability →

Sponsor

Air Liquide Santé International — full company profile →

Who can join

55 and older, any sex, with Hemodynamic Stability. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Standard deviation of the values of systolic blood pressure (SBP)collected per-operatively every minutes(BIOPAC ® MP150) Values of SBP over or under thresholds during and out of the clamping period, if so vasopressive/ hypotensive treatment used
Time frame: Pre-op, every min from 1-90 min during maintenance phase

Sponsor's own description

The purpose of this study is to compare the hemodynamics effects of two usual hypnotic agents (LENOXe ™ (xenon 100 % v/v) and sevoflurane) during a general anesthesia for carotid endarterectomy in elderly patients. The hypothesis is that the use of the LENOXe ™ (xenon 100 % v/v) allows to obtain per-operating hemodynamic stability non inferior than with sevoflurane.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Hemodynamic Stability

Currently open trials in the same condition.

NCT07365345 — Frequency of Electrical Acupoint Stimulation on Hypotension in TAVR Patients · NA · recruiting
NCT07138872 — Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy · NA · recruiting

Other Air Liquide Santé International trials

Trials by the same sponsor.

NCT05793645 — Clinical Investigation to Assess the Feasibility of a New Diabetes Management Program · NA · unknown
NCT05246449 — Evaluate the Benefit of an Individualised Treatment Plan (VitalCare) VS SOC in OSA Patients Treated With CPAP/APAP · NA · completed
NCT04635280 — Evaluation of Satisfaction Regarding Home Healthcare Provider (HHP) Management of Type 1 Diabetic Patients Using a Close · NA · completed
NCT04615078 — Study Evaluating Telemonitoring and Experimentation in Telemedicine for the Improvement of Healthcare Pathways (ETAPES P · NA · completed
NCT04233229 — Evaluation of a Closed-loop Insulin Delivery System at Home With Tailored Home Care Services in Poorly Controlled Type 2 · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT00937807 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Air Liquide Santé International
Last refreshed: 10 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT00937807.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing