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NCT00930657

CO2 Inhalation and Risk for Panic Disorder

Terminated Last updated 14 August 2019
What this trial tests

trial in Panic Disorder in 13 participants. Terminated before completion.

Timeline
26 June 2009
12 August 2019

Quick facts

Lead sponsorNational Institute of Mental Health (NIMH)
StatusTerminated
Study typeOBSERVATIONAL
Enrollment13
Start date26 June 2009
Estimated completion12 August 2019
Sites1 location across United States

Conditions studied

Sponsor

National Institute of Mental Health (NIMH)

Who can join

Adults 9 to 20, any sex, with Panic Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Objective: To examine respiratory/physiological and subjective responding as well as genetic transmission among offspring of parents with a history of or current panic disorder (PD) diagnosis to determine whether diagnoses/symptoms, endophenotypes, or genetic profiles in offspring is differentially related to parent PD subtypes (i.e., respiratory and non-respiratory panic). Study population: Approximately 400 offspring of about 200 parents with current or past PD. Approximately 200 offsping/100 parents with PD will be enrolled at NIH/NIMH and the remainder at Virginia Commonwealth University in Richmond, VA. Design: A high-risk family design will be used wherein parents with either a current or past diagnosis of PD who have an offspring(s) (ages 9 to 20) will be recruited. \<TAB\> Outcome measures: Outcome measures will include physiological recordings of respiratory, cardiac, and electrodermal responding during a 10 minute baseline followed by 15 minutes of 5% carbon dioxide enriched air (CO2). Research participants also will complete parent and child self-report measures and provide a DNA sample using a saliva protocol. A full listing of self-reports is provided in the Outcome Measures Section.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Panic Disorder

Currently open trials in the same condition.

Other National Institute of Mental Health (NIMH) trials

Trials by the same sponsor.

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Data sources for this page

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